Linfócitos T CD4: Th1 e Th2

th1  Th1 cells are a lineage of CD4 + effector T cell that promotes cell-mediated immune responses and is required for host defense against intracellular viral and Th1 cells play important roles in the identification and eradication of intracellular pathogens such as viruses and bacteria

TH1 is the base class of all histogram classes in ROOT Smooth bin contents of this histogram Returns the Standard Deviation For axis = 1,2 or 3 Th1 diseases are characterized by a strong Th1 response, while Th2 diseases are characterized by a weak or absent Th1 response Th1 cytokines like IFNγ and TNFα

Evidence is accumulating that Th1 cells play an important role in the development of multiple sclerosis and experimental allergic encephalomyelitis , In highly viremic animals, Th1 cells predominates over Th17 T cells and the frequency of Th17 cells at mucosal sites is negatively correlated with plasma virus